Detection of Breast Milk and Amniotic Fluid in Late Pregnant Women with Asymptomatic Infection of Coronavirus Disease 2019: Case Report

It was to explore the clinical characteristics of late pregnant women with asymptomatic infection of coronavirus disease 2019 (COVID-19) and the risk of intrauterine vertical transmission and breastfeeding transmission. The clinical data of a late pregnant woman with COVID-19 were retrospectively analyzed. The patient (singleton, cephalic) was admitted to the hospital on April 3, 2022. The patient had a dramatic increase in C-reactive protein after delivery, other blood routine tests were unremarkable, and the result of nucleic acid test was positive. On April 13, 2022, due to oligohydramnios, under measures such as positive pressure headgear and protective clothing in negative pressure operating room, second cesarean section combined with hysterorrhaphy (emergency) was performed to terminate the pregnancy, and the mother and baby were in good condition. Postpartum amniotic fluid, milk, and neonatal nucleic acid tests were negative. Corresponding treatment was given after cesarean section, and the patient was continuously monitored for nucleic acid detection to meet the discharge criteria of the COVID-19 and discharged and isolated. After discharge, the patient was followed up for 1 month. The newborn's spirit, diet, and development were normal. The maternal cesarean section incision recovered well. Patient with COVID-19 in the third trimester has prolonged hospital stays and are difficult to treat. However, the virus was not found in amniotic fluid, breast milk, and newborn, for which COVID-19 does not lead to intrauterine vertical transmission and breastfeeding transmission in the third trimester.Copyright © 2023 by the authors.

Persistent SARS-CoV-2 RNA Positive in Feces but Negative in Breastmilk: A Case Report of COVID-19 in a Breastfeeding Patient.

COVID-19 is a pandemic infectious disease. Whether SARS-CoV-2 was transmitted through breast milk is unknown. Here, we report a breastfeeding woman with COVID-19 presenting with gastrointestinal symptoms and persistent SARS-CoV-2 RNA positivity in both her oropharyngeal swabs and feces, but negativity in her breastmilk. After appearance of serum SARS-CoV-2-IgG, she began to bottle feed her baby with breastmilk without transmission. This report facilitates the understanding of breastfeeding-related risks in COVID-19.